Munguva pfupi yapfuura, hofori mbiri dzefodya, PMI neBAT, dzakatevedzana dzakaburitsa mapepa ekutsvagisa mumagazini epamusoro ezvekurapa epasi rose.Mhedzisiro yetsvagiridzo inoratidza kuti zvigadzirwa zvitsva zvefodya senge e-fodya uye kupisa-kwete-kupisa zvigadzirwa hazvina kukuvadza uye zvine muchetura kupfuura wefodya yechinyakare, uye zvinogona kuderedza zvakanyanya kukanganisa pakufema system.kukuvadza.
Sezvo kuziva kwevanhu nezvengozi yekusvuta kunowedzera, e-fodya iri kuramba ichizivikanwa sechinotsiva midzanga, asi mhedzisiro yenguva refu yemusanganiswa weflavored e-cigarette flavour uye utsi hwefodya kune vanoputa zvinoramba zvichiongororwa.Nguva pfupi yadarika, PMI Philip Morris International yakaburitsa gwaro rekutsvagisa "Kuongorora kwehupfu hwehupfu hwehutsi hwefodya uye aerosols kubva musanganiswa wekunhuhwirira: 5-vhiki yekudzidza muA/J mbeva" muBritish Journal yeToxicology "Journal of Applied Toxicolog", ichitsanangura zvese. yenyaya dzine hukama Matanho ekutsvagisa nemhedzisiro.
Mukuedza, 87 mbeva dzechirume uye 174 nulliparous uye mbeva dzechikadzi dzine nhumbu dzakapihwa zvisina tsarukano kumapoka ekuyedza 9, uye dzakaedzwa mumhepo, utsi hwefodya, uye e-fodya aerosols ane matatu akasiyana ekutarisisa, akakwirira, epakati, uye akaderera. .Kuratidzwa kusvika kumaawa matanhatu pazuva, mazuva mashanu pasvondo, kwemavhiki mashanu kwakateverwa necropsy, uremu hwenhengo uye histopathological assessment.
Mhedzisiro yekupedzisira yekuedza yakaratidza kuti kana ichienzaniswa nekufumurwa nehutsi hwefodya, mbeva dzakafumurwa kune e-cigarette aerosols ine uye isina zvinonhuwirira yakanga isina shanduko yakakosha munhengo dzekufema, mhino, uye laryngeal epithelial tishu, izvo zvakaratidza kuti e-fodya Iyo sol haina kutsamwisa. kune matishu uye nhengo dzinoenderana.Mhedzisiro yekuedza yakaratidza zvakare kuti, zvichienzaniswa nefodya yechinyakare, e-fodya inogona kuderedza zvakanyanya kuzvimba kwemapapu, pamwe nekukuvadzwa kweepithelium yemhino, huro uye trachea.
BAT yeBritish American Fodya yakaburitsa bepa rekutsvagisa rakanzi "An Experimental Analytical and In Vitro Approach to Bridge Pakati Pezvakasiyana Zvigadzirwa Zvefodya Yakapisa" mu "Mipiro kuFodya & Nekutsvagisa Nicotine" magazini yesainzi, uye yakaita tsvakiridzo paTHP (HNB zvigadzirwa) Toxicology. kuedza.Mukuyedza, aerosol nehutsi hwefodya hwemhando shanu dzeTHP uye imwe yakakosha THP yakashandiswa senzvimbo yekuyedza, uye cytotoxicity yakaongororwa nekushanda kwemaseru emapapu epithelial.Mhedzisiro yacho yakaratidza kuti maitiro ese ecytotoxic muboka reTHP angangoita 95% akaderera pane ayo ari muboka refodya, uye pakanga pasina musiyano wakakura muhuturu pakati peiyo shanu mutsauko THPs uye yakakosha THP.
Chidzidzo ichi chakagumisa kuti kuvandudzwa uye kupihwa kweimwe fodya uye nicotine zvigadzirwa zviri kukura nekukurumidza, vatengi vari kuramba vachigamuchira zvigadzirwa zvitsva zvakaita seTHP, uye kuchengetedzeka kwayo uye njodzi sechikamu chekuongorora toxicological kwakakodzera kutariswa neindasitiri.Chete kana chigadzirwa chasangana nezviyero (kusanganisira kuita kwebhatiri) zvinogona kuita zvirinani basa rayo rakanaka sechirongwa chehutano hweveruzhinji.
References:
Ee Tsin Wong,Karsta Luettich,Lydia Cammack,et al.Ongororo yekufemerwa kwehuturu hwehutsi hwefodya uye aerosols kubva musanganiswa wekunaka: 5-vhiki yekudzidza muA/J mbeva.Nyaya yeApped toxicolog, 2022
Tomasz Jaunky,David Thorne,Andrew Baxter,et al.Yekuedza Yekuongorora uye In Vitro Nzira yeBridge Pakati peMakasiyana Akasiyana Anopisa Chigadzirwa Chefodya.Mipiro kuFodya & Nicotine Research,2022.
Nguva yekutumira: Feb-01-2023
